Polymerases & Mixes

Drug-resistance mutation frequency of SGA-derived HIV-1 polymerase genomes

Drug-resistance mutation frequency of SGA-derived HIV-1 polymerase genomes

mytaq

Drug-resistance mutation frequency of SGA-derived HIV-1 polymerase genomes within the CSF and plasma of HIV-1-infected people underneath non-suppressive remedy

HIV-1 evolution within the CSF and plasma could end in discordant drug-resistance mutations (DRMs) within the compartments. Single genome amplification (SGA) was used to generate partial HIV-1 polymerase genomes in paired CSF and plasma from 12 HIV-1 constructive CHARTER contributors categorized as neurocognitively unimpaired or with numerous levels of HIV-Related Neurocognitive Issues (HAND).

 

  • Topics had been viremic on mixture antiretroviral remedy (cART). HIV-1 DRMs and phylogenetic traits had been decided utilizing the Stanford HIVdb program and phylogenetic analyses. Particular person DRMs had been recognized extra continuously in plasma than in paired CSF (p=0.0078).
  • Vital variations within the ratios of DRMs in CSF and plasma had been present in Three people with HAND (3/7=43%). 2 HAND topics (2/7=29%) demonstrated one DRM in CSF not recognized in paired plasma.
  • Longitudinal analyses (n=4) revealed vital temporal variations within the ratios of DRMs within the compartments. Statistically vital variations within the frequency of DRMs within the CSF and plasma are readily present in these on non-suppressive cART.
  • Whereas compartment-based DRM discordance was largely in line with elevated drug-selective pressures within the plasma, overrepresentation of DRMs within the CNS can happen. Underlying mechanisms of HAND are advanced and multifactorial.
  • The scientific affect of DRM discordance on viral persistence and HAND pathogenesis stays unclear and warrants additional investigation in bigger, longitudinal cohorts.

    Significance: A number of antiretroviral brokers don’t effectively enter the CNS and impartial evolution of HIV-1 viral variants within the CNS and plasma can happen.

  • We use single genome amplification (SGA) in cross-sectional and longitudinal analyses to uniquely outline each the id and relative proportions of drug resistance mutations (DRMs) on particular person HIV-1 pol genomes within the cerebrospinal fluid (CSF) and plasma in people with incomplete viral suppression and recognized neurocognitive standing. Statistically vital variations within the ratio of DRMs within the CSF and plasma had been readily present in these on non-suppressive cART and overrepresentation of DRMs within the CNS can happen.
  • Though questions concerning the scientific significance of DRM discordance stay, within the quest for viral eradication, you will need to acknowledge {that a} vital, dynamic, compartment-based DRM ratio imbalance can exist, because it has the potential to go unnoticed within the setting of ordinary scientific drug resistance testing.
mytaq
mytaq

DNA Polymerase Iota (POLI) Antibody

abx028115-400ul 400 ul
EUR 627.6

DNA Polymerase Iota (POLI) Antibody

abx028115-80l 80 µl
EUR 343.2

DNA Polymerase Iota (POLI) Antibody

20-abx323859
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

DNA Polymerase Iota (POLI) Antibody

20-abx001585
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Polymerase (Dna Directed) iota Antibody

20-abx114586
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

DNA Polymerase Iota (POLI) Antibody (HRP)

20-abx335403
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Polymerase Iota (POLI) Antibody (FITC)

20-abx335404
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Polymerase Iota (POLI) Antibody (Biotin)

20-abx335405
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA polymerase iota (POLI) polyclonal antibody

ABP-PAB-11630 100 ug Ask for price

Anti-DNA Polymerase iota/POLI Antibody

A01376-1 100ug/vial
EUR 352.8

Anti-DNA Polymerase iota (8G9)

YF-MA11349 100 ug
EUR 435.6
Description: Mouse monoclonal to DNA Polymerase iota

Human DNA Polymerase Iota (POLI) ELISA Kit

abx382346-96tests 96 tests
EUR 1093.2

Human DNA polymerase iota, POLI ELISA KIT

ELI-38100h 96 Tests
EUR 988.8

Mouse DNA polymerase iota, Poli ELISA KIT

ELI-12742m 96 Tests
EUR 1038

DNA Polymerase λ Antibody

34098-100ul 100ul
EUR 302.4

DNA Polymerase λ Antibody

34098-50ul 50ul
EUR 224.4

DNA Polymerase β Antibody

33357-100ul 100ul
EUR 302.4

DNA Polymerase β Antibody

33357-50ul 50ul
EUR 224.4

DNA Polymerase ζ Antibody

33602-100ul 100ul
EUR 302.4

DNA Polymerase ζ Antibody

33602-50ul 50ul
EUR 224.4

DNA Polymerase θ Antibody

33611-100ul 100ul
EUR 302.4

DNA Polymerase θ Antibody

33611-50ul 50ul
EUR 224.4

DNA Polymerase α Antibody

33665-100ul 100ul
EUR 302.4

DNA Polymerase α Antibody

33665-50ul 50ul
EUR 224.4

DNA polymerase beta Antibody

abx232432-100ug 100 ug
EUR 577.2

DNA Polymerase beta Antibody

AF0148 200ul
EUR 420

DNA Polymerase beta Antibody

49605-100ul 100ul
EUR 399.6

DNA Polymerase beta Antibody

49605-50ul 50ul
EUR 286.8

DNA Polymerase beta antibody

70R-31161 100 ug
EUR 392.4
Description: Rabbit polyclonal DNA Polymerase beta antibody

DNA Polymerase zeta antibody

70R-33711 100 ug
EUR 392.4
Description: Rabbit polyclonal DNA Polymerase zeta antibody

DNA Polymerase zeta antibody

70R-33727 100 ug
EUR 392.4
Description: Rabbit polyclonal DNA Polymerase zeta antibody

DNA Polymerase beta antibody

70R-50226 100 ul
EUR 292.8
Description: Purified Polyclonal DNA Polymerase beta antibody

DNA Polymerase beta Antibody

35404-100ul 100ul
EUR 468

DNA Polymerase beta Antibody

ABF0148 100 ug
EUR 525.6

DNA Polymerase beta Antibody

20-abx008852
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

DNA Polymerase beta Antibody

20-abx013060
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

DNA Polymerase beta Antibody

DF6552 200ul
EUR 420

DNA Polymerase gamma antibody

22870-100ul 100ul
EUR 468

DNA Polymerase alpha Antibody

AF5235 200ul
EUR 420

DNA polymerase gamma antibody

70R-12532 100 ul
EUR 548.4
Description: Affinity purified Rabbit polyclonal DNA polymerase gamma antibody

DNA Polymerase alpha antibody

70R-31578 100 ug
EUR 392.4
Description: Rabbit polyclonal DNA Polymerase alpha antibody

DNA Polymerase theta antibody

70R-33737 100 ug
EUR 392.4
Description: Rabbit polyclonal DNA Polymerase theta antibody

DNA Polymerase alpha Antibody

20-abx013375
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

DNA Polymerase alpha Antibody

DF3082 200ul
EUR 420

DNA Polymerase theta Antibody

DF13563 100ul
EUR 420

DNA Polymerase lambda antibody

70R-32186 100 ug
EUR 392.4
Description: Rabbit polyclonal DNA Polymerase lambda antibody

DNA Polymerase Mu (POLM) Antibody

abx236614-100ug 100 ug
EUR 661.2

DNA Polymerase Mu (POLM) Antibody

20-abx217851
  • EUR 510.00
  • EUR 410.40
  • 100 ug
  • 50 ug

DNA Polymerase Mu (POLM) Antibody

20-abx141146
  • EUR 427.20
  • EUR 644.40
  • EUR 260.40
  • 100 ul
  • 200 ul
  • 30 ul

DNA Polymerase Nu (POLN) Antibody

abx028202-400ul 400 ul
EUR 627.6

DNA Polymerase Nu (POLN) Antibody

abx028202-80l 80 µl
EUR 343.2

DNA Polymerase Mu (POLM) Antibody

20-abx323923
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

DNA Polymerase Eta (POLH) Antibody

abx117166-100ug 100 ug
EUR 560.4

DNA Polymerase Eta (POLH) Antibody

abx036483-100ug 100 ug
EUR 469.2

DNA Polymerase Eta (POLH) Antibody

20-abx001515
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Polymerase Eta (POLH) Antibody

20-abx302606
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA polymerase eta Antibody / POLH

R32359 100 ug
EUR 356.15
Description: DNA polymerase eta (POLH), is a protein that in humans is encoded by the POLH gene. This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene.

DNA Polymerase delta 3 antibody

70R-50825 100 ul
EUR 292.8
Description: Purified Polyclonal DNA Polymerase delta 3 antibody

DNA Polymerase alpha 1 antibody

70R-50225 100 ul
EUR 292.8
Description: Purified Polyclonal DNA Polymerase alpha 1 antibody

DNA Polymerase delta 1 antibody

70R-50227 100 ul
EUR 292.8
Description: Purified Polyclonal DNA Polymerase delta 1 antibody

DNA Polymerase delta 3 Antibody

20-abx008311
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

DNA Polymerase delta 1 Antibody

20-abx008851
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

DNA Polymerase alpha 1 Antibody

20-abx008853
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

anti- DNA polymerase beta antibody

FNab02432 100µg
EUR 606.3
Description: Antibody raised against DNA polymerase beta

DNA polymerase beta Antibody / POLB

R31898 100 ug
EUR 356.15
Description: Polymerase (DNA directed), beta, also known as POLB, is an enzyme that, in humans, is encoded by the POLB gene. It is localized on 8p11.2. The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. It is found that a truncated POLB is expressed in primary colorectal tumors and inhibits the normal repair function of wildtype POLB. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of this gene exist, but the full-length nature of only one has been described to date. Additionally, human POLB forms a complex with and is methylated by PRMT6. In vitro, methylated POLB possesses significantly higher DNA polymerase activity when compared to that of unmodified enzyme. The increase in DNA polymerase activity upon methylation is due to the enhanced DNA binding and processivity of POLB.

DNA Polymerase beta Antibody / POLB

RQ5162 100ul
EUR 356.15
Description: The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. [RefSeq]

DNA polymerase delta cat antibody

70R-12690 100 ul
EUR 548.4
Description: Affinity purified Rabbit polyclonal DNA polymerase delta cat antibody

Impact of sub-chronic publicity to cigarette smoke, digital cigarette and waterpipe on human lung epithelial barrier operate

Background: Making an allowance for a latest surge of a lung damage situation related to digital cigarette use, we devised an in vitro mannequin of sub-chronic publicity of human bronchial epithelial cells (HBECs) in air-liquid interface, to find out deterioration of epithelial cell barrier from sub-chronic publicity to cigarette smoke (CS), e-cigarette aerosol (EC), and tobacco waterpipe exposures (TW).

Strategies: Merchandise analyzed embrace commercially accessible e-liquid, with 0% or 1.2% focus of nicotine, tobacco mix (shisha), and reference-grade cigarette (3R4F). In a single set of experiments, HBECs had been uncovered to EC (Zero and 1.2%), CS or management air for 10 days utilizing 1 cigarette/day.

Within the second set of experiments, publicity of pseudostratified major epithelial tissue to TW or management air publicity was carried out 1-h/day, each different day, till Three exposures had been carried out.

After 16-18 h of final publicity, we investigated barrier operate/structural integrity of the epithelial monolayer with fluorescein isothiocyanate-dextran flux assay (FITC-Dextran), measurements of trans-electrical epithelial resistance (TEER), evaluation of the proportion of shifting cilia, cilia beat frequency (CBF), cell movement, and quantification of E-cadherin gene expression by reverse-transcription quantitative polymerase chain response (RT-qPCR).

Outcomes: When in comparison with air management, CS elevated fluorescence (FITC-Dextran assay) by 5.6 occasions, whereby CS and EC (1.2%) decreased TEER to 49 and 60% respectively. CS and EC (1.2%) publicity decreased CBF to 62 and 59%, and cilia shifting to 47 and 52%, respectively, when in comparison with management air. CS and EC (1.2%) elevated cell velocity in comparison with air management by 2.5 and a pair of.6 occasions, respectively.

The expression of E-cadherin decreased to 39% of management air ranges by CS publicity reveals an perception right into a believable molecular mechanism. Altogether, EC (0%) and TW exposures resulted in additional reasonable decreases in epithelial integrity, whereas EC (1.2%) considerably decreased airway epithelial barrier operate comparable with CS publicity.

Conclusions: The outcomes assist a poisonous impact of sub-chronic publicity to EC (1.2%) as evident by disruption of the bronchial epithelial cell barrier integrity, whereas additional analysis is required to handle the molecular mechanism of this statement in addition to TW and EC (0%) toxicity in persistent exposures.
Key phrases: Cigarette; Cilia; E-cadherin; E-cigarette; Nicotine; Tobacco; Waterpipe.

Anti-Taq DNA Polymerase Antibody

48369-50ul 50ul
EUR 286.8

anti- DNA polymerase beta antibody

FNab02432 100µg
EUR 606.3
Description: Antibody raised against DNA polymerase beta

DNA Polymerase λ Antibody

34098-100ul 100ul
EUR 302.4

DNA Polymerase λ Antibody

34098-50ul 50ul
EUR 224.4

DNA Polymerase β Antibody

33357-100ul 100ul
EUR 302.4

DNA Polymerase β Antibody

33357-50ul 50ul
EUR 224.4

DNA Polymerase ζ Antibody

33602-100ul 100ul
EUR 302.4

DNA Polymerase ζ Antibody

33602-50ul 50ul
EUR 224.4

DNA Polymerase θ Antibody

33611-100ul 100ul
EUR 302.4

DNA Polymerase θ Antibody

33611-50ul 50ul
EUR 224.4

Anti-POLK/Dna Polymerase Kappa Antibody

A01987 100ug
EUR 518.4
Description: Goat Polyclonal POLK/Dna Polymerase Kappa Antibody. Validated in WB and tested in Human.

DNA polymerase beta Antibody

abx232432-100ug 100 ug
EUR 577.2

DNA Polymerase beta Antibody

AF0148 200ul
EUR 420

DNA Polymerase beta Antibody

49605-100ul 100ul
EUR 399.6

DNA Polymerase beta Antibody

49605-50ul 50ul
EUR 286.8

DNA Polymerase beta antibody

70R-31161 100 ug
EUR 392.4
Description: Rabbit polyclonal DNA Polymerase beta antibody

DNA Polymerase zeta antibody

70R-33711 100 ug
EUR 392.4
Description: Rabbit polyclonal DNA Polymerase zeta antibody

DNA Polymerase zeta antibody

70R-33727 100 ug
EUR 392.4
Description: Rabbit polyclonal DNA Polymerase zeta antibody

DNA Polymerase beta antibody

70R-50226 100 ul
EUR 292.8
Description: Purified Polyclonal DNA Polymerase beta antibody

DNA Polymerase beta Antibody

35404-100ul 100ul
EUR 468

DNA Polymerase beta Antibody

ABF0148 100 ug
EUR 525.6

DNA Polymerase beta Antibody

20-abx008852
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

DNA Polymerase beta Antibody

20-abx013060
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

DNA Polymerase beta Antibody

DF6552 200ul
EUR 420

DNA Polymerase gamma antibody

22870-100ul 100ul
EUR 468

DNA Polymerase alpha Antibody

AF5235 200ul
EUR 420

DNA polymerase gamma antibody

70R-12532 100 ul
EUR 548.4
Description: Affinity purified Rabbit polyclonal DNA polymerase gamma antibody

DNA Polymerase alpha antibody

70R-31578 100 ug
EUR 392.4
Description: Rabbit polyclonal DNA Polymerase alpha antibody

DNA Polymerase theta antibody

70R-33737 100 ug
EUR 392.4
Description: Rabbit polyclonal DNA Polymerase theta antibody

DNA Polymerase alpha Antibody

20-abx013375
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

DNA Polymerase alpha Antibody

DF3082 200ul
EUR 420

DNA Polymerase theta Antibody

DF13563 100ul
EUR 420

Anti-Taq DNA Polymerase Conjugated Antibody

C48369 100ul
EUR 476.4

DNA Polymerase lambda antibody

70R-32186 100 ug
EUR 392.4
Description: Rabbit polyclonal DNA Polymerase lambda antibody

Anti-DNA polymerase eta Antibody

STJ502747 100 µg
EUR 571.2

Anti-DNA Polymerase thet Antibody

A02205 100ul
EUR 476.4
Description: Rabbit Polyclonal DNA Polymerase thet Antibody. Validated in IHC and tested in Human.

Anti-DNA polymerase beta antibody

PAab02432 100 ug
EUR 426

Anti-DNA polymerase theta antibody

STJ71548 100 µg
EUR 312

DNA Polymerase Mu (POLM) Antibody

abx236614-100ug 100 ug
EUR 661.2

DNA Polymerase Mu (POLM) Antibody

20-abx217851
  • EUR 510.00
  • EUR 410.40
  • 100 ug
  • 50 ug

DNA Polymerase Mu (POLM) Antibody

20-abx141146
  • EUR 427.20
  • EUR 644.40
  • EUR 260.40
  • 100 ul
  • 200 ul
  • 30 ul

DNA Polymerase Nu (POLN) Antibody

abx028202-400ul 400 ul
EUR 627.6

DNA Polymerase Nu (POLN) Antibody

abx028202-80l 80 µl
EUR 343.2

DNA Polymerase Mu (POLM) Antibody

20-abx323923
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

DNA Polymerase Eta (POLH) Antibody

abx117166-100ug 100 ug
EUR 560.4

DNA Polymerase Eta (POLH) Antibody

abx036483-100ug 100 ug
EUR 469.2

DNA Polymerase Eta (POLH) Antibody

20-abx001515
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Polymerase Eta (POLH) Antibody

20-abx302606
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA polymerase eta Antibody / POLH

R32359 100 ug
EUR 356.15
Description: DNA polymerase eta (POLH), is a protein that in humans is encoded by the POLH gene. This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene.

DNA Polymerase delta 3 antibody

70R-50825 100 ul
EUR 292.8
Description: Purified Polyclonal DNA Polymerase delta 3 antibody

DNA Polymerase alpha 1 antibody

70R-50225 100 ul
EUR 292.8
Description: Purified Polyclonal DNA Polymerase alpha 1 antibody

DNA Polymerase delta 1 antibody

70R-50227 100 ul
EUR 292.8
Description: Purified Polyclonal DNA Polymerase delta 1 antibody

DNA Polymerase delta 3 Antibody

20-abx008311
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

DNA Polymerase delta 1 Antibody

20-abx008851
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

DNA Polymerase alpha 1 Antibody

20-abx008853
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

DNA Polymerase Iota (POLI) Antibody

abx236612-100ug 100 ug
EUR 577.2

DNA Polymerase Iota (POLI) Antibody

20-abx333843
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Polymerase Iota (POLI) Antibody

abx036752-100ug 100 ug
EUR 469.2

DNA Polymerase Iota (POLI) Antibody

abx028115-400ul 400 ul
EUR 627.6

DNA Polymerase Iota (POLI) Antibody

abx028115-80l 80 µl
EUR 343.2

DNA Polymerase Iota (POLI) Antibody

20-abx323859
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

DNA Polymerase Iota (POLI) Antibody

20-abx001585
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Polymerase iota Antibody / POLI

RQ4298 100 ug
EUR 356.15
Description: DNA polymerase iota is an enzyme that in humans is encoded by the POLI gene. The protein encoded by this gene is an error-prone DNA polymerase involved in DNA repair. The encoded protein promotes DNA synthesis across lesions in the template DNA, which other polymerases cannot do. The encoded polymerase inserts deoxynucleotides across lesions and then relies on DNA polymerase zeta to extend the nascent DNA strand to bypass the lesion.

DNA polymerase beta Antibody / POLB

R31898 100 ug
EUR 356.15
Description: Polymerase (DNA directed), beta, also known as POLB, is an enzyme that, in humans, is encoded by the POLB gene. It is localized on 8p11.2. The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. It is found that a truncated POLB is expressed in primary colorectal tumors and inhibits the normal repair function of wildtype POLB. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of this gene exist, but the full-length nature of only one has been described to date. Additionally, human POLB forms a complex with and is methylated by PRMT6. In vitro, methylated POLB possesses significantly higher DNA polymerase activity when compared to that of unmodified enzyme. The increase in DNA polymerase activity upon methylation is due to the enhanced DNA binding and processivity of POLB.

DNA Polymerase beta Antibody / POLB

RQ5162 100ul
EUR 356.15
Description: The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. [RefSeq]

DNA polymerase delta cat antibody

70R-12690 100 ul
EUR 548.4
Description: Affinity purified Rabbit polyclonal DNA polymerase delta cat antibody

DNA polymerase delta p50 Antibody

DF13788 100ul
EUR 420

DNA Polymerase Kappa (POLK) Antibody

abx236613-100ug 100 ug
EUR 610.8

DNA Polymerase Kappa (POLK) Antibody

abx031322-400ul 400 ul
EUR 627.6

DNA Polymerase Kappa (POLK) Antibody

abx031322-80l 80 µl
EUR 343.2

DNA Polymerase Sigma (POLS) Antibody

abx029151-400ul 400 ul
EUR 627.6

DNA Polymerase Sigma (POLS) Antibody

abx029151-80l 80 µl
EUR 343.2

DNA Polymerase Kappa (POLK) Antibody

20-abx126383
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Polymerase Kappa (POLK) Antibody

20-abx126384
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Polymerase Kappa (POLK) Antibody

20-abx126385
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Polymerase Theta (POLQ) Antibody

20-abx322965
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

DNA Polymerase Kappa (POLK) Antibody

20-abx338646
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA Polymerase Theta (POLQ) Antibody

abx432614-200ul 200 ul
EUR 343.2

DNA Polymerase Kappa (POLK) Antibody

20-abx004686
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA Polymerase Theta (POLQ) Antibody

20-abx013320
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

anti-DNA polymerase? antibody (rabbit antiserum)

70-041 50uL
EUR 496.8
Description: The anti-DNA polymerase? antibody (rabbit antiserum) is available in Europe and for worldwide shipping via Gentaur.

DNA Polymerase Zeta (REV3L) Antibody

20-abx133309
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

DNA Polymerase epsilon 2 antibody

70R-50228 100 ul
EUR 292.8
Description: Purified Polyclonal DNA Polymerase epsilon 2 antibody

Human DNA Polymerase beta Antibody

33292-05111 150 ug
EUR 313.2

DNA Polymerase epsilon 2 Antibody

20-abx008850
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

DNA Polymerase Zeta (REV3L) Antibody

20-abx013311
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

DNA Polymerase Lambda (POLL) Antibody

20-abx217850
  • EUR 510.00
  • EUR 410.40
  • 100 ug
  • 50 ug

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