Western Blot – MyTaq

High-throughput screening to discover inhibitors of the CarD·RNA polymerase protein-protein interaction in Mycobacterium tuberculosis

Posted on December 10, 2020October 10, 2023

High-throughput screening to discover inhibitors of the CarD·RNA polymerase protein-protein interaction in Mycobacterium tuberculosis

Multidrug-resistant Mycobacterium tuberculosis (MDR-TB) accounts for 3.7% of recent instances of TB yearly worldwide and is a significant menace to world public well being. Because of the prevalence of the MDR-TB and extensively drug resistant…Continue Reading

Vancomycin-modified poly-l-lysine magnetic separation combined with multiplex polymerase chain reaction assay for efficient detection of Bacillus cereus in milk

Posted on December 10, 2020

Vancomycin-modified poly-l-lysine magnetic separation combined with multiplex polymerase chain reaction assay for efficient detection of Bacillus cereus in milk

On this research, a brand new vancomycin (Van)-modified poly-l-lysine (PLL) magnetic bead (MB) approach was developed for isolation of gram-positive micro organism. The strategy combines magnetic separation with a multiplex PCR (mPCR) assay and gel…Continue Reading

Combined inhibition of RNA polymerase I and mTORC1/2 synergize to combat oral squamous cell carcinoma

Posted on December 10, 2020

Combined inhibition of RNA polymerase I and mTORC1/2 synergize to combat oral squamous cell carcinoma

Oral squamous cell carcinoma (OSCC) is the key explanation for morbidity and mortality in head and neck most cancers sufferers worldwide. This malignant illness is difficult to deal with due to the dearth of efficient…Continue Reading

Revealing the Inhibition Mechanism of RNA-Dependent RNA Polymerase (RdRp) of SARS-CoV-2 by Remdesivir and Nucleotide Analogues: A Molecular Dynamics Simulation Study

Posted on December 10, 2020

Revealing the Inhibition Mechanism of RNA-Dependent RNA Polymerase (RdRp) of SARS-CoV-2 by Remdesivir and Nucleotide Analogues: A Molecular Dynamics Simulation Study

Antiviral drug remedy in opposition to SARS-CoV-2 just isn’t but established and posing a critical international well being difficulty. Remdesivir is the primary antiviral compound authorized by the US FDA for the SARS-CoV-2 remedy for…Continue Reading

Function of the Human RNA Polymerase II Transcription Machinery

Posted on August 22, 2020

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A Single-Molecule Floor-Primarily based Platform to Detect the Meeting and Operate of the Human RNA Polymerase II Transcription Equipment Single-molecule detection and manipulation is a robust device for unraveling dynamic organic processes. Sadly, success in…Continue Reading

Drug-resistance mutation frequency of SGA-derived HIV-1 polymerase genomes

Posted on August 22, 2020

mytaq

Drug-resistance mutation frequency of SGA-derived HIV-1 polymerase genomes within the CSF and plasma of HIV-1-infected people underneath non-suppressive remedy HIV-1 evolution within the CSF and plasma could end in discordant drug-resistance mutations (DRMs) within the…Continue Reading

Real-Time Polymerase chain response detection of bioterrorism menace

Posted on August 22, 2020

mytaq

Multi-platform comparability of ten industrial grasp mixes for probe-based real-time polymerase chain response detection of bioterrorism menace brokers for surge preparedness. The Facilities for Illness Management and Prevention and United States Military Analysis Institute for…Continue Reading

DNA Polymerase Facilitating Error-Prone DNA Damage Tolerance in Crenarchaeota

Posted on August 22, 2020

mytaq

A Distinctive B-Household DNA Polymerase Facilitating Error-Susceptible DNA Harm Tolerance in Crenarchaeota Sulfolobus islandicus codes for 4 DNA polymerases: three are of the B-family (Dpo1, Dpo2, and Dpo3), and one is of the Y-family (Dpo4). Western…Continue Reading

Polymerase chain reaction assay for specific detection of bocavirus-1

Posted on August 22, 2020

mytaq

TaqMan-based real-time polymerase chain response assay for particular detection of bocavirus-1 in home cats Feline bocavirus-1 (FBoV-1) was first found in Hong Kong in 2012, and research have indicated that the virus might trigger feline…Continue Reading

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