Polymerases & Mixes

Development of poly ADP-ribose polymerase-1 inhibitor with anti-cervical carcinoma activity

Development of poly ADP-ribose polymerase-1 inhibitor with anti-cervical carcinoma activity

Development of poly ADP-ribose polymerase-1 inhibitor with anti-cervical carcinoma activity

This analysis aimed to find and determine new poly ADP-ribose polymerase-1 (PARP) inhibitors with potent anti-cervical carcinoma exercise, after which discover their potential organic roles on cervical carcinoma cell. For this objective, we recognized a brand new PARP inhibitor from a high-throughput digital screening technique and located that the compound strongly inhibited cervical carcinoma HeLa cell. Cell proliferation was evaluated by an MTT assay, and the cell apoptosis was assessed by stream cytometry.

Outcomes confirmed that PARP1 is a poly ADP-ribose catalyzing enzyme in eukaryotic cells, which is activated throughout DNA harm and restore, and performs an vital function in DNA restore and cell apoptosis. Herein we report the primary discovery of a brand new PARP inhibitor from a high-throughput digital screening technique, then the compound was measured its anti-cervical carcinoma exercise through the use of an MTT assay, which instructed that the compound strongly inhibited HeLa cell proliferation, the IC50 worth is 0.65 µM. As well as, the compound induced HeLa cell apoptosis in a dose-response method. All these information instructed that the compound is a promising lead compound, which deserves additional investigation. It’s concluded that the compound uncover herein is a promising PARP-1 inhibitor with potent anti-cervical carcinoma exercise, which deserves additional investigation. Individuals residing in southwest a part of United States are uncovered to uranium (U) by means of ingesting water, air, and soil. U is radioactive, however impartial of this radioactivity additionally has vital toxicological issues as an environmental metallic.

At environmentally related concentrations, U is each mutagenic and carcinogenic. Rising proof exhibits that U inhibits DNA restore exercise, however how U interacts with DNA restore proteins continues to be largely unknown. Herein, we report that U instantly interacts with the DNA restore protein, Protein Poly (ADP-ribose) Polymerase 1 (PARP-1) by means of direct binding with the zinc finger motif, leading to zinc launch from zinc finger and DNA binding exercise lack of the protein. On the peptide stage, as a substitute of direct competitors with zinc ion within the zinc finger motif, U doesn’t present thermodynamic benefits over zinc. Moreover, zinc pre-occupied PARP-1 zinc finger is insensitive to U remedy, however U certain to PARP-1 zinc finger may be partially changed by zinc. These outcomes present mechanistic foundation on molecular stage to U inhibition of DNA restore.

 

Variety and Distribution of a Novel Genus of Hyperthermophilic Aquificae Viruses Encoding a Proof-Studying Household-A DNA Polymerase

Regardless of the excessive abundance of Aquificae in lots of geothermal methods, these micro organism are tough to tradition and no viruses infecting members of this phylum have been remoted. Right here, we describe the entire, round dsDNA Uncultivated Virus Genome (UViG) of Thermocrinis Octopus Spring virus (TOSV), derived from metagenomic information, together with eight associated UViGs representing three extra viral species. Regardless of low total similarity amongst viruses from completely different scorching springs, the genomes shared a excessive diploma of synteny, and encoded quite a few genes for nucleotide metabolism, together with a PolA-type DNA polymerase polyprotein with doubtless accent features, a DNA Pol III sliding clamp, a thymidylate kinase, a DNA gyrase, a helicase, and a DNA methylase.
Additionally current had been conserved genes predicted to code for phage capsid, giant and small subunits of terminase, portal protein, holin, and lytic transglycosylase, all per a distant relatedness to cultivated Caudovirales. These viruses are predicted to contaminate Aquificae, as a number of CRISPR spacers matching the viral genomes had been recognized inside the genomes and metagenomic contigs from these micro organism. Primarily based on the anticipated atypical bi-directional replication technique, low sequence similarity to recognized viral genomes, and distinctive place in gene-sharing networks, we suggest a brand new putative genus, “Pyrovirus,” within the order Caudovirales.
 Development of poly ADP-ribose polymerase-1 inhibitor with anti-cervical carcinoma activity
Development of poly ADP-ribose polymerase-1 inhibitor with anti-cervical carcinoma activity

Growth of Improved Mumps Vaccine Candidates by Mutating Viral mRNA Cap Methyltransferase Websites within the Giant Polymerase Protein

Though a dwell attenuated vaccine is out there for controlling mumps virus (MuV), mumps nonetheless outbreaks often worldwide. The attenuated MuV vaccine pressure S79 is extensively utilized in mumps vaccination in China, however nonetheless with many shortcomings, amongst which essentially the most outstanding are the uncomfortable side effects and decreased immunity.
Subsequently, there’s a must additional enhance the protection and efficacy of the present MuV vaccine. Within the current research, we additional attenuated MuV S79 vaccine pressure by inhibiting viral mRNA methyltransferase (MTase). We generated a panel of eight recombinant MuVs (rMuVs) carrying mutations within the MTase catalytic web site or S-adenosylmethionine (SAM) binding web site within the giant (L) polymerase protein. These rMuVs are genetically steady and 7 rMuVs are extra attenuated in replication in cell tradition and 5 rMuVs are extra attenuated in replication in lungs of cotton rats in contrast with the parental vaccine pressure S79.

DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (POLR2E) Antibody

20-abx001458
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (POLR2E) Antibody

20-abx121663
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (RPAB1) Antibody

20-abx119102
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (POLR2E) Antibody

20-abx114604
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (POLR2E) Antibody

abx028042-400ul 400 ul
EUR 627.6

DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (POLR2E) Antibody

abx028042-80l 80 µl
EUR 343.2

DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (POLR2E) Antibody

abx036186-100ug 100 ug
EUR 469.2

DNA-Directed RNA Polymerases I, II, And III Subunit RPABC2 (RPAB2) Antibody

20-abx217855
  • EUR 510.00
  • EUR 410.40
  • 100 ug
  • 50 ug

DNA-Directed RNA Polymerases I, II, And III Subunit RPABC4 (RPAB4) Antibody

20-abx217857
  • EUR 510.00
  • EUR 410.40
  • 100 ug
  • 50 ug

DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (POLR2E) Antibody

20-abx304890
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA-Directed RNA Polymerases I, II, And III Subunit RPABC4 (POLR2K) Antibody

20-abx304897
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Human RNA Polymerases I, II, III Subunit ABC3 (RPB17) Antibody

33234-05111 150 ug
EUR 313.2

Kluyveromyces marxianus DNA-directed RNA polymerases I, II, and III subunit RPABC1 (RPB5)

1-CSB-EP889203KAN
  • EUR 733.20
  • EUR 370.80
  • EUR 2192.40
  • EUR 1126.80
  • EUR 1461.60
  • EUR 476.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Kluyveromyces marxianus DNA-directed RNA polymerases I, II, and III subunit RPABC1(RPB5) expressed in E.coli

ELISA kit for Mouse DNA-directed RNA polymerases I and III subunit RPAC2 (POLR1D)

KTE71446-48T 48T
EUR 398.4
Description: Quantitative sandwich ELISA for measuring Mouse DNA-directed RNA polymerases I and III subunit RPAC2 (POLR1D) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse DNA-directed RNA polymerases I and III subunit RPAC2 (POLR1D)

KTE71446-5platesof96wells 5 plates of 96 wells
EUR 2538
Description: Quantitative sandwich ELISA for measuring Mouse DNA-directed RNA polymerases I and III subunit RPAC2 (POLR1D) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse DNA-directed RNA polymerases I and III subunit RPAC2 (POLR1D)

KTE71446-96T 96T
EUR 646.8
Description: Quantitative sandwich ELISA for measuring Mouse DNA-directed RNA polymerases I and III subunit RPAC2 (POLR1D) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat DNA-directed RNA polymerases I, II, and III subunit RPABC1 (POLR2E)

KTE100871-48T 48T
EUR 398.4
Description: Quantitative sandwich ELISA for measuring Rat DNA-directed RNA polymerases I, II, and III subunit RPABC1 (POLR2E) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat DNA-directed RNA polymerases I, II, and III subunit RPABC1 (POLR2E)

KTE100871-5platesof96wells 5 plates of 96 wells
EUR 2538
Description: Quantitative sandwich ELISA for measuring Rat DNA-directed RNA polymerases I, II, and III subunit RPABC1 (POLR2E) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat DNA-directed RNA polymerases I, II, and III subunit RPABC1 (POLR2E)

KTE100871-96T 96T
EUR 646.8
Description: Quantitative sandwich ELISA for measuring Rat DNA-directed RNA polymerases I, II, and III subunit RPABC1 (POLR2E) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Human RNA Polymerases I, II, III Subunit ABC3 (RPB17) Antibody (Biotin Conjugate)

33234-05121 150 ug
EUR 442.8

Human RNA Polymerases I, II, III Subunit ABC3 (RPB17) AssayLite Antibody (FITC Conjugate)

33234-05141 150 ug
EUR 513.6

Human RNA Polymerases I, II, III Subunit ABC3 (RPB17) AssayLite Antibody (RPE Conjugate)

33234-05151 150 ug
EUR 513.6

Human RNA Polymerases I, II, III Subunit ABC3 (RPB17) AssayLite Antibody (APC Conjugate)

33234-05161 150 ug
EUR 513.6

Human RNA Polymerases I, II, III Subunit ABC3 (RPB17) AssayLite Antibody (PerCP Conjugate)

33234-05171 150 ug
EUR 565.2

Human Kinase Library III

HKIN-III 1 set
EUR 540

anti-RNA polymerase III subunit C7

YF-PA17107 50 ul
EUR 435.6
Description: Mouse polyclonal to RNA polymerase III subunit C7

RNA Polymerase III Subunit H (POLR3H) Antibody

20-abx133433
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

RNA Polymerase III Subunit A (POLR3A) Antibody

20-abx133710
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

RNA Polymerase III Subunit B (POLR3B) Antibody

20-abx133711
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

RNA Polymerase III Subunit E (POLR3E) Antibody

20-abx133712
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

RNA Polymerase III Subunit K (POLR3K) Antibody

20-abx004958
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

RNA Polymerase III Subunit K (POLR3K) Antibody

20-abx007776
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

RNA Polymerase III Subunit C (POLR3C) Antibody

20-abx008319
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

RNA Polymerase III Subunit F (POLR3F) Antibody

20-abx008320
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

RNA Polymerase III Subunit G (POLR3G) Antibody

20-abx121198
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

RNA Polymerase III Subunit K (POLR3K) Antibody

abx122630-100ug 100 ug
EUR 469.2

RNA Polymerase III Subunit A (POLR3A) Antibody

20-abx126391
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

RNA Polymerase III Subunit F (POLR3F) Antibody

20-abx126392
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

RNA Polymerase III Subunit A (POLR3A) Antibody

20-abx114609
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

RNA Polymerase III Subunit D (POLR3D) Antibody

20-abx114611
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

RNA Polymerase III Subunit F (POLR3F) Antibody

20-abx114612
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

RNA Polymerase III Subunit K (POLR3K) Antibody

20-abx114613
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

RNA Polymerase III Subunit D (POLR3D) Antibody

abx027427-400ul 400 ul
EUR 627.6

RNA Polymerase III Subunit D (POLR3D) Antibody

abx027427-80l 80 µl
EUR 343.2

RNA Polymerase III Subunit B (POLR3B) Antibody

abx027628-400ul 400 ul
EUR 627.6

RNA Polymerase III Subunit B (POLR3B) Antibody

abx027628-80l 80 µl
EUR 343.2

RNA Polymerase III Subunit C (POLR3C) Antibody

abx029368-400ul 400 ul
EUR 627.6

RNA Polymerase III Subunit C (POLR3C) Antibody

abx029368-80l 80 µl
EUR 343.2

RNA Polymerase III Subunit E (POLR3E) Antibody

abx036024-100ug 100 ug
EUR 469.2

RNA Polymerase III Subunit D (POLR3D) Antibody

abx036131-100ug 100 ug
EUR 469.2

RNA Polymerase III Subunit B (POLR3B) Antibody

abx037547-100ug 100 ug
EUR 469.2

RNA Polymerase III Subunit H (POLR3H) Antibody

abx332717-100ul 100 ul
EUR 510

RNA Polymerase III Subunit B (POLR3B) Antibody

20-abx334341
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

RNA Polymerase III Subunit C (POLR3C) Antibody

abx331138-100ul 100 ul
EUR 510

RNA Polymerase III Subunit D (POLR3D) Antibody

abx331139-100ul 100 ul
EUR 510

RNA Polymerase III Subunit B (POLR3B) Antibody

abx331849-100ul 100 ul
EUR 510

RNA Polymerase III Subunit E (POLR3E) Antibody

20-abx217859
  • EUR 510.00
  • EUR 410.40
  • 100 ug
  • 50 ug

RNA Polymerase III Subunit E (POLR3E) Antibody

20-abx301672
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

RNA Polymerase III Subunit F (POLR3F) Antibody

20-abx302688
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

RNA Polymerase III Subunit A (POLR3A) Antibody

20-abx304901
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

RNA Polymerase III Subunit C (POLR3C) Antibody

20-abx323956
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

RNA Polymerase III Subunit G (POLR3G) Antibody

20-abx325515
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

RNA Polymerase III Subunit D (POLR3D) Antibody

20-abx325565
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

RNA Polymerase III Subunit E (POLR3E) Antibody

20-abx326196
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

RNA Polymerase III Subunit A (POLR3A) Antibody

20-abx326317
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

RNA Polymerase III Subunit B (POLR3B) Antibody

20-abx328661
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

RNA Polymerase III Subunit H (POLR3H) Antibody

20-abx328796
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

RNA Polymerase III Subunit A (POLR3A) Antibody

abx236629-100ug 100 ug
EUR 610.8

RNA Polymerase III Subunit B (POLR3B) Antibody

abx236630-100ug 100 ug
EUR 610.8

RNA Polymerase III Subunit D (POLR3D) Antibody

abx236631-100ug 100 ug
EUR 610.8

RNA Polymerase III Subunit F (POLR3F) Antibody

abx236632-100ug 100 ug
EUR 610.8

RNA Polymerase III Subunit G (POLR3G) Antibody

abx236633-100ug 100 ug
EUR 661.2

RNA Polymerase III Subunit K (POLR3K) Antibody

abx236634-100ug 100 ug
EUR 577.2

Anti-Pig Collagen I and III antibody

STJ16101183 1 mL
EUR 457.2

Anti-Calf Collagen I and III antibody

STJ16101184 1 mL
EUR 457.2

Anti-Dog Collagen I and III antibody

STJ16101185 1 mL
EUR 457.2

Anti-Human Collagen I and III antibody

STJ16101366 100 µg
EUR 645.6

Navy RNA Lysis Kit 50

NAVYE1-RNA 50pack
EUR 237.6
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

Navy RNA Lysis Kit 250

NAVYE5-RNA 250pack
EUR 781.2
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

Green RNA Lysis Kit 50

GREENE1-RNA 50pack
EUR 216
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free.

Green RNA Lysis Kit 250

GREENE5-RNA 250pack
EUR 685.2
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free.

Pink RNA Lysis Kit 50

PINKE1-RNA 50pack
EUR 213.6
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Pink RNA Lysis Kit 250

PINKE5-RNA 250pack
EUR 673.2
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Red RNA Lysis Kit 50

REDE1-RNA 50pack
EUR 230.4
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Red RNA Lysis Kit 250

REDE5-RNA 250pack
EUR 746.4
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

YELLOW RNA Lysis Kit 50

YELLOWE1-RNA 50pack
EUR 230.4
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

YELLOW RNA Lysis Kit 250

YELLOWE5-RNA 250pack
EUR 748.8
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

RapidSeq High Yield Small RNA Sample Prep Kit - With Aligner 25-36

KS074012-III 1 Kit
EUR 1225.2
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

RNA Polymerase III Subunit K (POLR3K) Antibody (Biotin)

20-abx105351
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

RNA Polymerase III Subunit K (POLR3K) Antibody (FITC)

20-abx106770
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

RNA Polymerase III Subunit B (POLR3B) Antibody (HRP)

20-abx335439
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

RNA Polymerase III Subunit B (POLR3B) Antibody (FITC)

20-abx335440
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

RNA Polymerase III Subunit B (POLR3B) Antibody (Biotin)

20-abx335441
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

RNA Polymerase III Subunit A (POLR3A) Antibody (HRP)

20-abx304902
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

RNA Polymerase III Subunit A (POLR3A) Antibody (FITC)

20-abx304903
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

RNA Polymerase III Subunit A (POLR3A) Antibody (Biotin)

20-abx304904
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

RNA Polymerase III Subunit F (POLR3F) Antibody (HRP)

20-abx311789
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

RNA Polymerase III Subunit F (POLR3F) Antibody (FITC)

20-abx311790
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

RNA Polymerase III Subunit F (POLR3F) Antibody (Biotin)

20-abx311791
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

RNA Polymerase III Subunit E (POLR3E) Antibody (HRP)

20-abx311025
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

RNA Polymerase III Subunit E (POLR3E) Antibody (FITC)

20-abx311026
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

RNA Polymerase III Subunit E (POLR3E) Antibody (Biotin)

20-abx311027
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

RNA Polymerase I Subunit D (POLR1D) Antibody

20-abx142151
  • EUR 444.00
  • EUR 727.20
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 50 ul

RNA Polymerase I Subunit D (POLR1D) Antibody

20-abx006253
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

RNA Polymerase I Subunit C (POLR1C) Antibody

20-abx000654
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

RNA Polymerase II Subunit I (POLR2I) Antibody

20-abx001539
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

RNA Polymerase I Subunit A (POLR1A) Antibody

20-abx008213
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

RNA Polymerase I Subunit C (POLR1C) Antibody

20-abx008410
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

RNA Polymerase II Subunit I (POLR2I) Antibody

20-abx008848
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

RNA Polymerase I Subunit A (POLR1A) Antibody

20-abx124591
  • EUR 493.20
  • EUR 710.40
  • 100 ul
  • 200 ul

RNA Polymerase I Subunit C (POLR1C) Antibody

abx116999-100ug 100 ug
EUR 560.4
Importantly, cotton rats vaccinated with these seven rMuV mutants produced excessive ranges of serum neutralizing antibodies and had been utterly protected towards problem with a wild-type MuV pressure (genotype F). Subsequently, our outcomes show that alteration within the MTase catalytic web site or SAM binding web site in MuV L protein improves the protection or the immunogenicity of the MuV vaccine and thus mRNA cap MTase could also be an efficient goal for the event of recent vaccine candidates for MuV.

Leave a Reply

Your email address will not be published.