Polymerases & Mixes

Development of poly ADP-ribose polymerase-1 inhibitor with anti-cervical carcinoma activity

Development of poly ADP-ribose polymerase-1 inhibitor with anti-cervical carcinoma activity

Development of poly ADP-ribose polymerase-1 inhibitor with anti-cervical carcinoma activity

This analysis aimed to find and determine new poly ADP-ribose polymerase-1 (PARP) inhibitors with potent anti-cervical carcinoma exercise, after which discover their potential organic roles on cervical carcinoma cell. For this objective, we recognized a brand new PARP inhibitor from a high-throughput digital screening technique and located that the compound strongly inhibited cervical carcinoma HeLa cell. Cell proliferation was evaluated by an MTT assay, and the cell apoptosis was assessed by stream cytometry.

Outcomes confirmed that PARP1 is a poly ADP-ribose catalyzing enzyme in eukaryotic cells, which is activated throughout DNA harm and restore, and performs an vital function in DNA restore and cell apoptosis. Herein we report the primary discovery of a brand new PARP inhibitor from a high-throughput digital screening technique, then the compound was measured its anti-cervical carcinoma exercise through the use of an MTT assay, which instructed that the compound strongly inhibited HeLa cell proliferation, the IC50 worth is 0.65 µM. As well as, the compound induced HeLa cell apoptosis in a dose-response method. All these information instructed that the compound is a promising lead compound, which deserves additional investigation. It’s concluded that the compound uncover herein is a promising PARP-1 inhibitor with potent anti-cervical carcinoma exercise, which deserves additional investigation. Individuals residing in southwest a part of United States are uncovered to uranium (U) by means of ingesting water, air, and soil. U is radioactive, however impartial of this radioactivity additionally has vital toxicological issues as an environmental metallic.

At environmentally related concentrations, U is each mutagenic and carcinogenic. Rising proof exhibits that U inhibits DNA restore exercise, however how U interacts with DNA restore proteins continues to be largely unknown. Herein, we report that U instantly interacts with the DNA restore protein, Protein Poly (ADP-ribose) Polymerase 1 (PARP-1) by means of direct binding with the zinc finger motif, leading to zinc launch from zinc finger and DNA binding exercise lack of the protein. On the peptide stage, as a substitute of direct competitors with zinc ion within the zinc finger motif, U doesn’t present thermodynamic benefits over zinc. Moreover, zinc pre-occupied PARP-1 zinc finger is insensitive to U remedy, however U certain to PARP-1 zinc finger may be partially changed by zinc. These outcomes present mechanistic foundation on molecular stage to U inhibition of DNA restore.

 

Variety and Distribution of a Novel Genus of Hyperthermophilic Aquificae Viruses Encoding a Proof-Studying Household-A DNA Polymerase

Regardless of the excessive abundance of Aquificae in lots of geothermal methods, these micro organism are tough to tradition and no viruses infecting members of this phylum have been remoted. Right here, we describe the entire, round dsDNA Uncultivated Virus Genome (UViG) of Thermocrinis Octopus Spring virus (TOSV), derived from metagenomic information, together with eight associated UViGs representing three extra viral species. Regardless of low total similarity amongst viruses from completely different scorching springs, the genomes shared a excessive diploma of synteny, and encoded quite a few genes for nucleotide metabolism, together with a PolA-type DNA polymerase polyprotein with doubtless accent features, a DNA Pol III sliding clamp, a thymidylate kinase, a DNA gyrase, a helicase, and a DNA methylase.
Additionally current had been conserved genes predicted to code for phage capsid, giant and small subunits of terminase, portal protein, holin, and lytic transglycosylase, all per a distant relatedness to cultivated Caudovirales. These viruses are predicted to contaminate Aquificae, as a number of CRISPR spacers matching the viral genomes had been recognized inside the genomes and metagenomic contigs from these micro organism. Primarily based on the anticipated atypical bi-directional replication technique, low sequence similarity to recognized viral genomes, and distinctive place in gene-sharing networks, we suggest a brand new putative genus, “Pyrovirus,” within the order Caudovirales.
 Development of poly ADP-ribose polymerase-1 inhibitor with anti-cervical carcinoma activity
Development of poly ADP-ribose polymerase-1 inhibitor with anti-cervical carcinoma activity

Growth of Improved Mumps Vaccine Candidates by Mutating Viral mRNA Cap Methyltransferase Websites within the Giant Polymerase Protein

Though a dwell attenuated vaccine is out there for controlling mumps virus (MuV), mumps nonetheless outbreaks often worldwide. The attenuated MuV vaccine pressure S79 is extensively utilized in mumps vaccination in China, however nonetheless with many shortcomings, amongst which essentially the most outstanding are the uncomfortable side effects and decreased immunity.
Subsequently, there’s a must additional enhance the protection and efficacy of the present MuV vaccine. Within the current research, we additional attenuated MuV S79 vaccine pressure by inhibiting viral mRNA methyltransferase (MTase). We generated a panel of eight recombinant MuVs (rMuVs) carrying mutations within the MTase catalytic web site or S-adenosylmethionine (SAM) binding web site within the giant (L) polymerase protein. These rMuVs are genetically steady and 7 rMuVs are extra attenuated in replication in cell tradition and 5 rMuVs are extra attenuated in replication in lungs of cotton rats in contrast with the parental vaccine pressure S79.

DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (POLR2E) Antibody

20-abx304890
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA-Directed RNA Polymerases I, II, And III Subunit RPABC4 (POLR2K) Antibody

20-abx304897
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (POLR2E) Antibody

20-abx001458
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (POLR2E) Antibody

abx036186-100ug 100 ug
EUR 391

DNA-Directed RNA Polymerases I, II, And III Subunit RPABC3 (RPAB3) Antibody

20-abx149876
  • EUR 425.00
  • EUR 342.00
  • 100 ug
  • 50 ug

DNA-Directed RNA Polymerases I, II, And III Subunit RPABC4 (POLR2K) Antibody

20-abx135780
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DNA-Directed RNA Polymerases I, II, And III Subunit RPABC4 (POLR2K) Antibody

20-abx007835
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (POLR2E) Antibody

abx028042-400ul 400 ul
EUR 523

DNA-Directed RNA Polymerases I, II, And III Subunit RPABC1 (POLR2E) Antibody

abx028042-80l 80 µl
EUR 286

DNA-Directed RNA Polymerases I, II, And III Subunit RPABC2 (RPAB2) Antibody

20-abx217855
  • EUR 425.00
  • EUR 342.00
  • 100 ug
  • 50 ug

DNA-Directed RNA Polymerases I, II, And III Subunit RPABC4 (RPAB4) Antibody

20-abx217857
  • EUR 425.00
  • EUR 342.00
  • 100 ug
  • 50 ug

Human RNA Polymerases I, II, III Subunit ABC3 (RPB17) Antibody

33234-05111 150 ug
EUR 261

Kluyveromyces marxianus DNA-directed RNA polymerases I, II, and III subunit RPABC1 (RPB5)

1-CSB-EP889203KAN
  • EUR 611.00
  • EUR 309.00
  • EUR 1827.00
  • EUR 939.00
  • EUR 1218.00
  • EUR 397.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Kluyveromyces marxianus DNA-directed RNA polymerases I, II, and III subunit RPABC1(RPB5) expressed in E.coli

ELISA kit for Mouse DNA-directed RNA polymerases I and III subunit RPAC2 (POLR1D)

KTE71446-48T 48T
EUR 332
Description: Quantitative sandwich ELISA for measuring Mouse DNA-directed RNA polymerases I and III subunit RPAC2 (POLR1D) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse DNA-directed RNA polymerases I and III subunit RPAC2 (POLR1D)

KTE71446-5platesof96wells 5 plates of 96 wells
EUR 2115
Description: Quantitative sandwich ELISA for measuring Mouse DNA-directed RNA polymerases I and III subunit RPAC2 (POLR1D) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse DNA-directed RNA polymerases I and III subunit RPAC2 (POLR1D)

KTE71446-96T 96T
EUR 539
Description: Quantitative sandwich ELISA for measuring Mouse DNA-directed RNA polymerases I and III subunit RPAC2 (POLR1D) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat DNA-directed RNA polymerases I, II, and III subunit RPABC1 (POLR2E)

KTE100871-48T 48T
EUR 332
Description: Quantitative sandwich ELISA for measuring Rat DNA-directed RNA polymerases I, II, and III subunit RPABC1 (POLR2E) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat DNA-directed RNA polymerases I, II, and III subunit RPABC1 (POLR2E)

KTE100871-5platesof96wells 5 plates of 96 wells
EUR 2115
Description: Quantitative sandwich ELISA for measuring Rat DNA-directed RNA polymerases I, II, and III subunit RPABC1 (POLR2E) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat DNA-directed RNA polymerases I, II, and III subunit RPABC1 (POLR2E)

KTE100871-96T 96T
EUR 539
Description: Quantitative sandwich ELISA for measuring Rat DNA-directed RNA polymerases I, II, and III subunit RPABC1 (POLR2E) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Human RNA Polymerases I, II, III Subunit ABC3 (RPB17) Antibody (Biotin Conjugate)

33234-05121 150 ug
EUR 369

Human RNA Polymerases I, II, III Subunit ABC3 (RPB17) AssayLite Antibody (FITC Conjugate)

33234-05141 150 ug
EUR 428

Human RNA Polymerases I, II, III Subunit ABC3 (RPB17) AssayLite Antibody (RPE Conjugate)

33234-05151 150 ug
EUR 428

Human RNA Polymerases I, II, III Subunit ABC3 (RPB17) AssayLite Antibody (APC Conjugate)

33234-05161 150 ug
EUR 428

Human RNA Polymerases I, II, III Subunit ABC3 (RPB17) AssayLite Antibody (PerCP Conjugate)

33234-05171 150 ug
EUR 471

Human Kinase Library III

HKIN-III 1 set
EUR 450

anti-RNA polymerase III subunit C7

YF-PA17107 50 ul
EUR 363
Description: Mouse polyclonal to RNA polymerase III subunit C7

RNA Polymerase III Subunit A (POLR3A) Antibody

20-abx126391
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

RNA Polymerase III Subunit F (POLR3F) Antibody

20-abx126392
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

RNA Polymerase III Subunit G (POLR3G) Antibody

20-abx121198
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

RNA Polymerase III Subunit K (POLR3K) Antibody

abx122630-100ug 100 ug
EUR 391

RNA Polymerase III Subunit A (POLR3A) Antibody

20-abx114609
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

RNA Polymerase III Subunit D (POLR3D) Antibody

20-abx114611
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

RNA Polymerase III Subunit F (POLR3F) Antibody

20-abx114612
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

RNA Polymerase III Subunit K (POLR3K) Antibody

20-abx114613
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

RNA Polymerase III Subunit C (POLR3C) Antibody

20-abx323956
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

RNA Polymerase III Subunit A (POLR3A) Antibody

20-abx304901
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

RNA Polymerase III Subunit K (POLR3K) Antibody

20-abx004958
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

RNA Polymerase III Subunit E (POLR3E) Antibody

abx036024-100ug 100 ug
EUR 391

RNA Polymerase III Subunit D (POLR3D) Antibody

abx036131-100ug 100 ug
EUR 391

RNA Polymerase III Subunit B (POLR3B) Antibody

abx037547-100ug 100 ug
EUR 391

RNA Polymerase III Subunit H (POLR3H) Antibody

20-abx133433
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

RNA Polymerase III Subunit A (POLR3A) Antibody

20-abx133710
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

RNA Polymerase III Subunit B (POLR3B) Antibody

20-abx133711
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

RNA Polymerase III Subunit E (POLR3E) Antibody

20-abx133712
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

RNA Polymerase III Subunit K (POLR3K) Antibody

20-abx007776
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

RNA Polymerase III Subunit C (POLR3C) Antibody

20-abx008319
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

RNA Polymerase III Subunit F (POLR3F) Antibody

20-abx008320
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

RNA Polymerase III Subunit D (POLR3D) Antibody

abx027427-400ul 400 ul
EUR 523

RNA Polymerase III Subunit D (POLR3D) Antibody

abx027427-80l 80 µl
EUR 286

RNA Polymerase III Subunit C (POLR3C) Antibody

abx029368-400ul 400 ul
EUR 523

RNA Polymerase III Subunit C (POLR3C) Antibody

abx029368-80l 80 µl
EUR 286

RNA Polymerase III Subunit B (POLR3B) Antibody

abx027628-400ul 400 ul
EUR 523

RNA Polymerase III Subunit B (POLR3B) Antibody

abx027628-80l 80 µl
EUR 286

RNA Polymerase III Subunit A (POLR3A) Antibody

abx236629-100ug 100 ug
EUR 509

RNA Polymerase III Subunit B (POLR3B) Antibody

abx236630-100ug 100 ug
EUR 509

RNA Polymerase III Subunit D (POLR3D) Antibody

abx236631-100ug 100 ug
EUR 509

RNA Polymerase III Subunit F (POLR3F) Antibody

abx236632-100ug 100 ug
EUR 509

RNA Polymerase III Subunit G (POLR3G) Antibody

abx236633-100ug 100 ug
EUR 551

RNA Polymerase III Subunit K (POLR3K) Antibody

abx236634-100ug 100 ug
EUR 481

RNA Polymerase III Subunit E (POLR3E) Antibody

20-abx301672
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

RNA Polymerase III Subunit F (POLR3F) Antibody

20-abx302688
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

RNA Polymerase III Subunit E (POLR3E) Antibody

20-abx217859
  • EUR 425.00
  • EUR 342.00
  • 100 ug
  • 50 ug

RNA Polymerase III Subunit C (POLR3C) Antibody

abx331138-100ul 100 ul
EUR 425

RNA Polymerase III Subunit D (POLR3D) Antibody

abx331139-100ul 100 ul
EUR 425

RNA Polymerase III Subunit B (POLR3B) Antibody

abx331849-100ul 100 ul
EUR 425

RNA Polymerase III Subunit H (POLR3H) Antibody

abx332717-100ul 100 ul
EUR 425

RNA Polymerase III Subunit E (POLR3E) Antibody

20-abx326196
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

RNA Polymerase III Subunit A (POLR3A) Antibody

20-abx326317
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

RNA Polymerase III Subunit B (POLR3B) Antibody

20-abx328661
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

RNA Polymerase III Subunit H (POLR3H) Antibody

20-abx328796
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

RNA Polymerase III Subunit B (POLR3B) Antibody

20-abx334341
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

RNA Polymerase III Subunit G (POLR3G) Antibody

20-abx325515
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

RNA Polymerase III Subunit D (POLR3D) Antibody

20-abx325565
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

AC1 Antibody

1-CSB-PA324434LA01ADX
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against AC1. Recognizes AC1 from African cassava mosaic virus. This antibody is Unconjugated. Tested in the following application: ELISA

Anti-Pig Collagen I and III antibody

STJ16101183 1 mL
EUR 381

Anti-Calf Collagen I and III antibody

STJ16101184 1 mL
EUR 381

Anti-Dog Collagen I and III antibody

STJ16101185 1 mL
EUR 381

Anti-Human Collagen I and III antibody

STJ16101366 100 µg
EUR 538

Navy RNA Lysis Kit 50

NAVYE1-RNA 50pack
EUR 198
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

Navy RNA Lysis Kit 250

NAVYE5-RNA 250pack
EUR 651
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

Green RNA Lysis Kit 50

GREENE1-RNA 50pack
EUR 180
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free.

Green RNA Lysis Kit 250

GREENE5-RNA 250pack
EUR 571
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free.

Pink RNA Lysis Kit 50

PINKE1-RNA 50pack
EUR 178
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Pink RNA Lysis Kit 250

PINKE5-RNA 250pack
EUR 561
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

YELLOW RNA Lysis Kit 50

YELLOWE1-RNA 50pack
EUR 192
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

YELLOW RNA Lysis Kit 250

YELLOWE5-RNA 250pack
EUR 624
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Red RNA Lysis Kit 50

REDE1-RNA 50pack
EUR 192
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Red RNA Lysis Kit 250

REDE5-RNA 250pack
EUR 622
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

5E Navy RNA Lysis Kit 100

NAVY5E100-RNA 100pack
EUR 453
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 100, 5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

5E Navy RNA Lysis Kit 20

NAVY5E20-RNA 20pack
EUR 153
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

Navy RINO RNA Lysis Kit 50

NAVYR1-RNA 50pack
EUR 202
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stainless steel beads. RNase free.

Navy RINO RNA Lysis Kit 250

NAVYR5-RNA 250pack
EUR 666
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stainless steel beads. RNase free.

5E GREEN RNA Lysis Kit 100

GREEN5E100-RNA 100pack
EUR 386
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 1000, 5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free.

5E GREEN RNA Lysis Kit 20

GREEN5E20-RNA 20pack
EUR 138
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free.

Green RINO RNA Lysis Kit 50

GREENR1-RNA 50pack
EUR 184
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with beads. RNase free.

Green RINO RNA Lysis Kit 250

GREENR5-RNA 250pack
EUR 587
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with beads. RNase free.

5E PINK RNA Lysis Kit 100

PINK5E100-RNA 100pack
EUR 380
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 100, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

5E PINK RNA Lysis Kit 20

PINK5E20-RNA 20pack
EUR 136
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Pink RINO RNA Lysis Kit 50

PINKR1-RNA 50pack
EUR 181
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

Pink RINO RNA Lysis Kit 250

PINKR5-RNA 250pack
EUR 576
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

YELLOW RINO RNA Lysis Kit 50

YELLOWR1-RNA 50pack
EUR 199
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

YELLOW RINO RNA Lysis Kit 250

YELLOWR5-RNA 250pack
EUR 656
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

5E RED RNA Lysis Kit 100

RED5E100-RNA 100pack
EUR 429
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 100, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

5E RED RNA Lysis Kit 20

RED5E20-RNA 20pack
EUR 148
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Red RINO RNA Lysis Kit 50

REDR1-RNA 50pack
EUR 195
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

Red RINO RNA Lysis Kit 250

REDR5-RNA 250pack
EUR 638
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

RNA Polymerase III Subunit K (POLR3K) Antibody (FITC)

20-abx106770
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

RNA Polymerase III Subunit E (POLR3E) Antibody (HRP)

20-abx311025
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

RNA Polymerase III Subunit E (POLR3E) Antibody (FITC)

20-abx311026
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

RNA Polymerase III Subunit E (POLR3E) Antibody (Biotin)

20-abx311027
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

RNA Polymerase III Subunit F (POLR3F) Antibody (HRP)

20-abx311789
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
Importantly, cotton rats vaccinated with these seven rMuV mutants produced excessive ranges of serum neutralizing antibodies and had been utterly protected towards problem with a wild-type MuV pressure (genotype F). Subsequently, our outcomes show that alteration within the MTase catalytic web site or SAM binding web site in MuV L protein improves the protection or the immunogenicity of the MuV vaccine and thus mRNA cap MTase could also be an efficient goal for the event of recent vaccine candidates for MuV.

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